World news – Tracking the launch of SA’s Covid-19 vaccine

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The government is working to ensure that 67% of the population will be vaccinated by the end of 2021.

In other words, over a nine month period, the government expects 40 million citizens to be vaccinated, distributed and vaccinated.

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The government is the only purchaser of Covid-19 vaccines. However, the vaccines must first be approved for use by the SA Health Products Regulatory Authority (Sahpra). Sahpra’s mission is to regulate all health products and clinical trials in South Africa.

Sahpra reported that as of December 2, 2020, there were only 58 Covid-19 vaccine candidates in clinical research worldwide. Of these, 43 are in Phase I-II studies, 15 are in Phase II-III studies, and no vaccine has yet fully completed a Phase III study.

On January 22, 2021, Sahpra issued Section 21 (unregistered drug) approval to the Covishield Department of Health. Covishield is made by the Serum Institute of India and is the local name for the Oxford-AstraZeneca vaccine developed in the UK.

However, the use of the AstraZeneca vaccine has been temporarily suspended pending its effectiveness against the new Covid-19 501Y.V2 variant.

Recent reports summarized in The Lancet show that the vaccine is more effective when the second dose is given 12 weeks after the first.

As the doses received from South Africa have an expiration date of April 16, only one dose can be administered.

Minister of Health Dr. Zweli Mkhize tweeted on February 10th: « What will happen to the current doses of the AstraZeneca vaccine in SA depends on the advice of leading scientists. »

South Africa sourced nine million doses of the Johnson & Johnson (J&J) vaccine, and 80,000 doses arrived on February 16. Another 500,000 cans are expected to arrive over the next four weeks.

Sahpra approved the J&J vaccine for emergency use, 300,000 doses of which had already been tested and approved by the SA Health Products Regulatory Authority (Sahpra) for use under study conditions.

« The vaccine is being carried out in the form of an implementation study through a partnership between the SA Medical Research Council and the National Department of Health. » According to a media statement from the Ministry of Health on February 16.

Mkhize said in his address at the debate on the State of the Nation address by the President (Sona21): “As a government, we are actively engaging manufacturers and suppliers of Covid-19 vaccines through various but interconnected channels.  »

He added: “This includes the Covax facility, bilateral agreements with pharmaceutical companies and other mechanisms such as the African Union Vaccine Funding Strategy and the Vaccine Acquisition Task Team. These initiatives have so far allowed us to work with the manufacturers of several vaccines, namely AstraZeneca, Pfizer, Johnson & Johnson, Moderna, Sinopharm, Sinovac and Sputnik V.

« We recently had a discussion with Cuba to encourage them to develop their vaccine candidate. »

Mkhize also said the government has committed to sourcing 20 million doses of the Pfizer vaccine, which is expected to arrive in late March. No information was given on the authorization to use this vaccine.

Sahpra confirmed in a February 18 press release that it had not received any documentation for the Sputnik V vaccine developed by the Gamaleya Institute in Russia.

The batch of 80,000 J&J vaccines was approved by Sahpra under the Sisonke Protocol to gain an understanding of the effects of mass vaccination.

The Sisonke Early Access program started on February 17th (according to a media statement from the Ministry of Health dated February 21, 2021).

By February 21, 10,000 healthcare workers had been vaccinated with the J&J vaccine, which provides 57% protection against moderate to severe illness, 85% protection against serious illness, and 100% protection against death in clinical trials South African participants ????.

Sahpra approved the protocol amendment to the J&J Implementation Study for Health Care Workers (HCW) involving the President and Vice President, stating in a February 18 press release, “Although they are not classified as HCW Initiative would go a long way in promoting vaccine uptake and reducing vaccine hesitation.  »

President Cyril Ramaphosa, in response to the Sona21 debate, praised the global leadership skills of South African scientists, research institutions, universities, agencies and public institutions.

The South African scientists, engineers and manufacturers who were able to design and manufacture personal protective equipment and thousands of medical ventilators within a few months were recognized.

The President also paid tribute to the University of KwaZulu-Natal scientists who, in collaboration with other laboratories, have been at the forefront of the genomic surveillance work that has led to the identification of new Covid-19 variants. ?. He added, « South African scientists and researchers at a number of world-class institutions have been involved in managing vaccine trials in the country. »

Realizing that pandemics could be more common, the President suggested that South Africa develop its scientific skills and prepare for the future.

Ramaphosa mentioned that he had asked the Minister for Higher Education and Innovation « to put together a team of scientists to begin developing their own vaccines against this and future pandemics ».

For the latest information on Covid-19, please visit the Department of Health’s SA Coronavirus website. This includes Mkhize’s address to the Sona21 debate.

Detailed funding allocations for the procurement of Covid-19 vaccines will be announced in the state budget 2021 on Wednesday (February 24th).

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Hasn’t Vice President Mabuza been appointed head of vaccine distribution?
Shouldn’t he be announcing this « Sisonke » program? What has apparently been put together without consulting others outside of the same « experts » who have done « excellent » work so far on this front … Bravo!

This is convincing evidence of how quickly things dissolve when this clueless one ANC does things. And for those of us who have more brain cells than Zuma can count (it’s not much), you know problems lie ahead!

« Realizing that pandemics could be more common, the President suggested that that South Africa continues to develop its scientific skills and prepare for the future. « 

Geez, the IYI in the laboratories will surely make more fatal mistakes if the fools in this one get a pass.

A quick first look on the title « Covid-19 from Tracking SA … » led me astray to think:

(IF there was ever such a tracking fund, I wonder how the « Total Expense Ratio « (TER)? Maybe your » cost « includes two shots of the upper arm?

Puhleaaase !!
40 m by the end of the year. If we start tomorrow, that means 130,000 a day every day. With a bit of luck it might be possible on the subways, but if I were a bettor …
This is due to a concealment that, after many years, still fails on less complex issues such as testing and renewing driving and vehicle licenses, licensing and renewing firearms, an adequate level of math and science education, and much more.
At least they will buy us time so that the vaccines can be further refined …

Assuming the general vaccine is launched on April 1st, 2021 with a single shot of J&J. This requires approximately 4.44 million doses administered monthly across SA.

If you consider 60 doses as the minimum per site (this is the target per vaccine the nurse is administering), there are 2469 sites at 7 Used days a week for an average month of 30 days. That is low nationwide. If you take into account the private pharmacy, hospital groups, mobile stations, etc.

I still don’t see a big problem. Yes there will be distribution issues that need to be resolved (more for rural climates – electricity) but if done with the help of private sector it is mostly in urban & semi-urban areas where 2/3 of the population alive, manageable.

Personally, I think the bigger problem that is to come is vaccination refusal, which is already growing among different people from religious to so-called « smart ». People who are epically stupid when it comes to statistics and immunology, which is not their core competency.

Look, the government will always do what the government does. It’s like death and taxes. The question is how other parties react. That is, they play a supporting role. Or do they continue to be a disruptive force because they politically want to gain brownie points. So far, people seem to like killing their support base just to be against the government, which is weird since the result is that they are relegated to the insane end of the population.

Delusions. The ANC has the least ability to administer a vaccination program. They should outsource the entire program to the great able Israelis – and pay them in uranium.

Great summary of what looks like an overall clusterffff. Perhaps the « obscure little communications company » named by Zweli, which scored over 82 million points from the DoH for pandemic communications, will explain how the DoH will get 40 million vaccinated by Christmas … It will surely be a big win …

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